Pharmaceutical Analysis: A Textbook for Pharmacy Students and Pharmaceutical Chemists - No Cost Library

Pharmaceutical Analysis: A Textbook for Pharmacy Students and Pharmaceutical Chemists

Author(s): David G. Watson BSc Ph.D. PGCE

Publisher: Churchill Livingstone, Year: 1999 

Description:

Pharmaceutical Analysis: A Textbook for Pharmacy Students and Pharmaceutical Chemists features the most significant parts of a wide scope of procedures utilized in the control of the nature of pharmaceuticals, including spectroscopy, chromatography, and electrophoresis. This reasonable, handy guide likewise incorporates self-testing segPharmaceutical Analysis: A manual for Pharmacy Students and Medicinal Chemists contains the most important aspects of a broad variety of techniques used in medicinal function regulation, including spectroscopy, chromatography, and electrophoresis. This fair, convenient guide often includes parts of self-testing and arithmetic templates and measures in an implemented environment to assist understudies in looking at their arithmetic capability.ments and arithmetical models and tests to assist understudies with looking over their arithmetical abilities in an applied setting.

Book Review:

Extraordinary scientific developments tend to influence Pharmaceutical research. As a result, the challenge facing today's students in the pharmaceutical sciences is to keep pace with rapidly evolving methodology while mastering fundamental concepts in analytical chemistry. The Pharmaceutical Analysis textbook: A textbook for students of pharmacy and pharmaceutical chemists (2nd edition) helps students meet this challenge by striking a fine balance between theory and application.

The textbook begins with a chapter on the quality assurance of scientific processes and effective data collection. The next chapter focuses on the physicochemical properties of drug molecules including equilibria of acid-base, partitioning, degradation kinetics and stereochemistry. Chapter 3 offers an in-depth overview of titrimetric approaches ( e.g., acid-base, argentimetric, iodometric, and REDOX titrations), with focus on how these approaches are applicable to medication and excipient pharmacopoeial assays. Chapters 4 through 9 cover a wide range of spectral techniques: spectrophotometry (ultraviolet / visible, infrarot, radioactive emission / absorption, fluorescence), Raman spectroscopy, spectroscopy of nuclear magnetic resonance and mass spectrometry. Chapters 10 through 15 allow for thorough analysis of methods of separation, including chromatography (GC, HPLC, TLC), capillary electrophoresis, and extraction.

In Pharmaceutical Research the arrangement of topics is rational. For example, absorbance phenomena are grouped before fluorescence-based approaches, and chapters on specific chromatographic methods precede a section on the general separation theory. Each chapter begins with a sketch of the topics to be covered and "keypoints," including analytical techniques applications, strengths and weaknesses. Throughout the end of each chapter is given a list of sources, further reading, and related web pages. The author uses a remarkable number of specific, drug related examples to demonstrate the power of each method in the pharmaceutical sciences as an analytical tool. The text is also well illustrated with chemical formulas, instrumentation diagrams, and scientific data charts. In each chapter, reasonably challenging set of problems (provided with answers) allow students to fine-tune their mathematical and problem-solving skills.

Pharmaceutical analyzes are remarkable because they demonstrate developments applicable to the pharmaceutical sciences. Students reading this textbook should get to learn the effect of analytical chemistry on product detection, quantification, and separation. An important strength of this book is that a compromise between theory and application is skilfully achieved. Chemical and physical principles are presented with an appropriate level of sophistication, which allows the reader to grasp theoretical underpinnings of the analytical methods without being overwhelmed by excessive detail. At the same time, practical issues related to instrument design or data analysis are addressed in sufficient detail so that students understand how specific approaches are used in pharmaceutical sciences to solve real problems.

There are also drawbacks of pharmaceutical research, some of which can represent spatial constraints. Unlike other references to analytical chemistry, for example, there is very little content related to electrochemical analyses. There is also no mention of clinically applicable analytical instruments, as a textbook designed for pharmacy students would seem fitting. Additionally, tables of physical and chemical constants are not used, so further self-testing tests would help those parts. For these purposes, students and teachers may sometimes find additional sources appropriate to complement this text. Perhaps the most significant weakness throughout the textbook is the presence of several errors and typos.


On balance, Pharmaceutical Analysis is an excellent textbook that stands out due to its theoretical and implementation harmony, and its focus on examples specific to pharmacy. This book will be a very useful resource for undergraduate or graduate-level introductory students taking pharmaceutical analysis courses. Instructors of these courses should recommend adding this textbook to their list, without hesitation.